Klatskin tumor symptoms rarely show due to their location deep within the abdominal cavity. When a tumor is blocking the bile duct and preventing it from draining properly, people will then begin to develop Klatskin tumor symptoms related to that obstruction. Klatskin tumor symptoms typically include jaundice extreme yellowing of the skin , clay-colored stools due to lack of bile drainage into the digestive system , bilirubinuria dark urine , itchy skin, weight loss, and abdominal pain. Jaundice is usually the symptom prompting a person to seek medical attention. Treatment Options for Klatskin Tumors The primary goal of treatment and therapy for Klatskin cancer is the removal of the diseased tissue and relief of biliary blockages due to tumor formations, though Klatskin tumors are rare and have limited treatment options.
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These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional. This website is maintained by the National Library of Medicine. The National Cancer Institute provides the most current information on cancer for patients, health professionals, and the general public.
In-Depth Information Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free. The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers.
This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health.
Visit the website to explore the biology of this condition. Access to this database is free of charge. PubMed is a searchable database of medical literature and lists journal articles that discuss Klatskin tumor. Click on the link to view a sample search on this topic. We remove all identifying information when posting a question to protect your privacy.
If you do not want your question posted, please let us know. Submit a new question My mom has been diagnosed with a Klatskin tumor. They tried to remove it but were unable to do so. What symptoms might develop as her condition progresses? Her eyesight has become blurred. Could this be related to her condition? See answer.
All types of cancerous growth in the biliary duct are termed as cholangiocarcinoma. History Altemei, the great surgeon, and clinical educator first described the cancerous growth at the bifurcated junction of the biliary duct in Etiology The etiology of the Klatskin Tumor is not evident based. Multiple pathological conditions, which cause acute or chronic ailments of the biliary tract may have the influence to develop a malignant growth. The idiopathic cause of the development of primary sclerosing cholangitis has a direct association of Klatskin Tumor.
Tumor de Klatskin
Cause[ edit ] The cause of cholangiocarcinoma has not been defined. A number of pathologic conditions, however, resulting in either acute or chronic biliary tract epithelial injury may predispose to malignant change. These conditions appear to be related to an anomalous pancreatico-biliary duct junction and, perhaps, are related to the reflux of pancreatic secretions into the bile duct. Chronic biliary tract parasitic infection, seen commonly in Southeast Asia due to Clonorchis sinensis and Opisthorchis viverrini , has also been identified as a risk factor. Further, industrial exposure to asbestos and nitrosamines , and the use of the radiologic contrast agent, Thorotrast thorium dioxide , are considered to be risk factors for the development of cholangiocarcinoma. Diagnosis[ edit ] Levels of the tumor markers carbohydrate antigen CA , carcinoembryonic antigen CEA and CA are abnormally high in the bloodstreams of patients with intrahepatic cholangiocarcinoma and Klatskin tumor. The serum CA in particular may be very high.
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